PW01-022 – Dissociation between CRP and SAA in FMF
نویسندگان
چکیده
Methods CRP and SAA were systematically measured during the follow-up of consecutive attack-free FMF outpatients seen in a pediatric and an adult French reference center. Dissociations between CRP and SAA were defined by normal CRP (<5mg/L) and elevated SAA (group A), or elevated CRP and normal SAA (<10mg/L) (group B). Demographic data, genotype, clinical characteristics of FMF, and treatment were analyzed.
منابع مشابه
PW01-009 – Markers of inflammation in adult FMF patients
Methods 40 consecutive patients suffering from FMF according to the Livneh criteria and 40 healthy controls (C) were included into the study in Herne, Germany. All participants were Turkish migrants aged ≥18 years. Patients were excluded if they reported symptoms of FMF ≤7 days prior to inclusion. Frequency of FMF attacks during the 3 months preceding the study inclusion was assessed. Patients ...
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Results A total amount of 50 patients (22 girls, 28 boys) were included. The median age of the patients was 8.5 years (2.5-17.5). 78% of the patients suffered from fever attacks suggestive of FMF every 1-4 weeks. The attack interval of the remaining patients was more than one month. At the time of admission, the median values for ESR and CRP were; 24.5 mm/hr (1-100) and 2 mg/dl (0-31), respecti...
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Background and Objectives. SAA is an acute-phase reactant detected during an FMF attack or other inflammatory conditions. High SAA levels may increase the risk of amyloidosis. The aim of the study is to measure the serum amyloid A (SAA) level in a group of Egyptian children with familial Mediterranean fever (FMF) and study its various correlates, if any. Methods. The study enrolled seventy-one ...
متن کاملCan serum amyloid a level be used to support the Familial Mediterranean Fever diagnosis?
Introduction Familial Mediterranean Fever (FMF) is a periodic fever syndrome characterized by recurrent episodes of fever and serosal inflammation .The diagnosis is still based on clinical criteria. No laboratory test is diagnostic of FMF. During the attacks increased C reactive protein (CRP), serum amyloid A (SAA), fibrinogen, beta 2 microglobulin, erythrocyte sedimentation rate (ESR) and leuk...
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